They got him to eat a little the next morning and sent him home. Consulting vet and will not give Simparica ever again. It's only available with a prescription from your veterinarian, so you cannot get it over-the-counter. Yea so what about the 10 percent? So sorry to hear, and good for you in recognizing the problem! It really helped us to put this diarrhea condition in perspective. Pyrantel only treats parasites found in the gastrointestinal tract because it does not absorb well into the bloodstream. All we want to do is take the best care of our animals and trust the people (Vet's) who specialize in this to do what's right for them. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. Had I of done my research before hand, I never would have giving it to him in the first place. Will be talking to the vet inregards to his side effects. I have another dog, but gave him Frontline and he's fine. I would find another vet for a second opinion. He wouldnt survive surgical attempt to go in and try to figure out what was going on. My dog is currently in an emergency hospital in Chicago with my daughter. And urinating more often as a result. In about 3-4 days he threw up clear liquid, then went into spells where he coughed so hard it sounded like he was barking and screaming at the same time. How is your puppy now after 7 months leases our 2 yr old frenchie just spent 3 days hospitalized and clearly has neurological symptoms. It has been 20 days since I gave her the prescribed dose of Simparica. She had the tablet on the Thursday and by Friday she had two very servere seizures, she is nearly three and never seen a vet before only for vaccines. Manufactured by Zoetis, Simparica Trio contains three drugs: sarolaner, moxidectin, and pyrantel pamoate. He was in excellent health prior to this incident. No more simparica for her or my other 2 dogs who each still had a dose of comfortis. Im beside myself with guilt and fear. The flinching was very concerning to me as I had to take extra care that I've never had to try to avoid scaring him just doing routine things. Took a dose of simparica trio.second rose in second month.dog is having tremors. She has episodes where she seems very anxious and is hiding under car/tables/beds. My best friend's new puppy has had diarrhea for 14 days after taking one dose of Simparica. Now I have to pay $100's of dollars on meds to check her antibody and possibly put her on meds for life . I've tried Gatorade and Ginger ale but he only drank a little. This may post twice - I didn't see my original post so I'm trying again! Also - do NOT use Bravecto for females you intend to breed. 1 is pregnant I told the vet what can I give the pregnant yorkie she said sampirica sold me a 3 month supple for her. I realized it was from the simparica. There is NO other explanation for this rapid decline and the only change has been THIS drug. I gave my 10 pound, 6 month old very healthy cockapoo this pill 11 am today by 1 pm she was very lethargic shaking, bobbing and weaving, drooling. All went well until this morning. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. Sarolaner, one of the ingredients, is a member of the isoxazoline class. When GABA attaches to a protein in your brain known as a GABA receptor, it produces a calming effect. Do you have contact details that you can share with me. I won't sleep until we all get the justice for our babies that don't have voices of their own. The Vet's are so busy that even if you can get in you don't get anywhere. Simparica has possibly shown no severe side effects that may concern the health of dogs. But you can use a collar or topical for ticks if needed. Does your do still have a cough? I had placed an order with Pet Meds for the prescription before I saw any of these side effects.I will be returning this medication and order Heartgard and not sure what we will do for flea and ticks, since he turns his nos Simparica Trio, e to the Nexgard and we really dont feel safe with our Grandson around the topical or collarAny suggestions? I gave my black lab mix Simparica for the 1st time on 4/1. We were so upset - I vowed to never use oral flea treatment again. In such cases, please visit the veterinarian as soon as possible. This is because it doesn't kill adult heartworms. A month later, he was at doggie daycare and we picked him up and he was panting frantically. The Simparica chewable is a poor choice for dogs with a history of prior seizures. Those jaw spasms have decreased but were pretty alarming in Dec and January. I went and picked her up today and all she does is lay around and drink water, turns her nose up at anything food related. She has what is called knuckling. Moxidectin was first approved by the FDA in 1997 for the prevention of heartworm disease in dogs. She spent 4 nights at the University of Auburn emergency room and vet clinic. Read package insert - yes was tested on female dogs who were bred. I will post an update 7 days later. I took my dog to the vet today and she received fluids and gabapentin. I hate that I did this to her and I hate that the Vet does not seem to care. I read all the above and it makes me sad. After reading all of supporting reviews, I will never give him this again. If so how long did it take? Hes very lethargic and constant vomiting! Sarolaner is also used in combination products for both dogs and cats. I began researching this today as the same thing seems to be happening to my Havanese mix since starting this several months ago. How is your cockapoo doing now? But now I tell everyone just be aware that this product does have the potential to cause neurological harm. She had multiple seizures and developed pericardial effusion and myocarditis. What are the side effects of Simparica trio for dogs? He has been low energy since. I went to banfield hospital and they prescribed this medication for my dog and had thrown up non stop since he was given the pill and wouldnt eat anything and he passed away 10 days later (yesterday). Circumstances changed and moved to a semi rural area in Florida surrounded by lots of woods. The neurologist I went to would not give him steroids until I did the spinal tap and MRI. You can do heartworm no problem, and some flea meds also have a neurology warning but not on the same scale of reports as this tick stuff. Went to a different vet, within minutes he found a large mass on my Poms abdomen. I recently switched my 3.5 year old German Shepard to simparica and about 2 weeks after his first dose he had two seizures in one night and has NEVER had them before. I gave 2 of my older Labs a dose of Simparica on a Saturday. Also I read on Dr Mercola site that heartworms is in the dogs blood not the digestive track and garlic won't work. All said, we are over $8K into vet bills and growing, Given that he had no noted medical issues prior, his vet and the urgent care vet both feel is was likely the Simparico. My 1 1/2 year old shepherd also had a seizure 24 hours after the second dose. org to have this poison recalled. Tuesday morning she woke up with horrible diarrhea. Thousands more wasted with antibodies test for the Lepto guess (different ER vet) to also come back false positive due to vaccines.. my poor baby already had a rough life being abandoned. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrheaboth symptoms related to Fidos digestive tract, rather than his nervous system. No more of this junk for my pups! Then he starts scratching and as time goes on he seemed like something was wrong. And yeah he ate today 4 chicken breast and appeared to want it even better. Then we seen an ad on tv for Simparica and it mentioned seizures as a side effect. How is your puppy doing? I even told them about the Simparica which they dont respond to. How do I get this out of his system and what are you using instead? Although vet wanted to treat him for Addison's I decided to wait it out and fortunately it worked out. Hi i have only had my pup for about a week and a half i took him to vet and asked what would be safe to use since my pup is only about 11weeks old and weighs 4pds (prob less today) i gave him this medicine last nite and wish i would have seen this post sooner Now i pray he makes it thru the night. Always confirm storage temperatures by reading the label. Your veterinarian is the best source of information and will help you choose the right product for your dog and your budget. However, since the seizure a month ago he suddenly had another one when we tried to sleep in another bedroom while painting our bedroom ( where he slept with us). . I hope this comment will save you and your pets from unnecessary trouble. Chewable tablets can be given directly to your dog or broken up and mixed with food. We contacted the company using the phone number supplied in the under in the box and shared our experience with the new drug. My dog has been vomiting with diarrhea plus he has bumps all over his body from one dose of simparica trio. Never again will I be giving my pets any pharma meds. We may also give additional medications to keep fleas, ticks, and common intestinal parasites away. She is more worried about excessive thirst, lip smacking and her kidneys. Im beside myself. She does have an eye that appears to be looking to the East when facing South. Ticks are horrible here in Maine. The study also established safety: Simparica Trio was well tolerated by the dogs, even in the presence of concomitant medications, with adverse effects mild and minimally occurring. I also changed him over to a raw diet a few weeks ago too have taken him off of this again to see if raw diet is causing it. Stay safe! Did the tremors ever stop? Vet says not to go back to Any brand oral flea/tick meds, so well be using Frontline drops on her shoulders from now on. 98. Could this be caused by the med? Today really soft stool (not diarrhea but close). He has been resting most of the day so far, thankfully no seizures.. but I promise I will not be giving him the other 2 doses I got from the vet after reading all of the experiences everyone else has had with their animals. Im petrified after reading the comments here. Just hoping you can give me something good and tell me your dog recovered. He had gone to a new groomer and when he came home he had a seizure. Now that Ive read all these comments I think he has developed these issues because of this trio medication. Simparica is available in different doses for dogs 2.8 pounds and over, but has not been evaluated for use in pregnant, breeding or nursing pets. I am so upset - I gave it to him last week and he had an accident in the house. Gave our Bloodhound Simparico Trip on Tuesday on Thursday he got extremely thirsty and was peeing everywhere from drinking so much water. Lost his appetite & was low on energy all day yesterday, slept most of the day - which is very unusual for him. Two quick questionsDo the dogs eventually return to normal? Got a new GS when the old one died. Simparica Trio covers the most common dog parasites and typically costs less than buying separate products. He's a 1 1/2 y.o. I feel so dumb for taking him off of something that we had no problems with and it worked fine, just to try something new that he didn't need. For those who lost their dear companions from this medicine my heart goes out to you all. I dont know what to do to get this out of their system?? I used to use revolution but they dont cover ticks as well. In addition to killing fleas and several kinds of ticks, Simparicais effective in preventing and treating mange and ear mites. I to also gave my best friend Simparica as recommended by the vet. Hi how is your pup now? She had terrible watery diarrhea and is not interested in eating. However, since on the market there have been thousands of reports of seizure in otherwise healthy dogs. I could never forgive myself. Gave this flea medicine today and by 10 pm toy poodle having siesures every 3-10 seconds. That night he seemed a little uncomfortable, unable to sleep, and I didnt think anything of it. Hi Laura, How is you pup doing one after getting off simparica? Any believers out there please say a prayer for our pup as I will for the people on this thread. I was reading that this drug enters the bloodstream quickly after giving it, and these symptoms and all the other reports have convinced me that I'm done using this on my pup. I know Dukes problems were from this medicine, and it upsets me that my vet told me that this medicine was safe! Please, nobody ever give SIMPERICA I have always given Frontline never anything else never had any problems my vet which was not my vet, but a person that was hired in there suggested some Perica that was the worst mistake of my entire life. We have been gradually increasing the dose but it hasnt helped. Has anyone experienced cardiac issues while under anesthesia on this medication? Really angry this drug is on the market and pushed by many vets. Wont use again. He has been using Simparica Trio since it came out several years ago, which eliminates the need for an additional monthly heart guard chewable. So new pup goes on garlic tabs-as he growing I'm upping the amount because I wanted him to be protected. This time he just kept collapsing, bloated appearing, vomit, and diarrhea, and hiding with his face down and nose in carpet. I'm so sorry. Charlie took the pill on Monday and could not even walk this morning. Currently we are monitoring him closely-hes never been sick. Today March 20 (8 week old) I get a message saying the puppy ate one of these pills that was for the bigger dog she already owned. I hope this product is no longer sold anywhere. Anything I can do for him? She vomited twice and became so lethargic that she couldnt walk. supply) at Chewy.com. I would, still boil chicken, carrots, potatoes for his meals. Around 9pm he was barely able to jump up onto the couch and was extremely hesitant to go up the steps. My dog weighs 60 pounds and was given a dose for dogs up to 88 pounds. She is lethargic and doesnt want to eat. Vet says garlic doesn't work and obviously it didn't because he shaved a little of dogs fur and put it on a paper towels and it was full of fleas.The vet gives me Simpirica-ok fleas are dropping off him like crazy. Even when we specifically mentioned the new information he still had nothing but the original tests to go off of. Our dog had her first dose June 1st 2022 - diarrhea, scratching, excessive thirst. This is lethal medication for dogs and should be taken off the market now. She had a beautiful coat of fur. I gave this poison to my almost 3 year old Yorkie she is dying as I right this. I immediately filed a case number with Zoetis and informed my Vet as well as current Vet hospital he is being held at. In addition to the tremors, have you noticed any . Our pick for best oral flea control product for dogs is Simparica TRIO, a chewable tablet that is fast-acting and kills more parasites than any other oral product. He is fully housebroken and just had a running stool accident in the house. Seizure meds arent working. I will not give it to my puppy again, but what is a safer med. The main side effect of Simparica Trio is the risk of heartworm disease in dogs. Other signs may include: Lethargy Loss of appetite Our two year old dog took the same thing and thank god she has no symptoms. Our dog has had 2 Seizures this month and we are going to stop using Simparica. Itching has decreased immensely. I dont want to have to put my dog down but hes suffering. I am so worried after reading these comments. She couldnt walk straight anymore and stopped eating. I gave our boy, Yogi his first dose of Simparica TRIO on 11/17/2020. Vet said they dont think it has anything to do with the Simparica. He is 11 so I attributed his slowing down on walks to aging but now he is recently limping and at times has some trouble with jumping up on the bed. Fortunately, no seizures but dark yellow diarrhea and puppy has been drinking water like crazy and peeing even while asleep. My shepherd got it the following month and I called the vet again and she prescribed probiaotics and anti diarrhea meds again. He also got that odd cough here and there that I read someone else mention. We think that the drug is the cause of the seizures . like what??? He is otherwise normal and healthy. Twice I have seen his eyes roll into the back of his head (petti-mal seizure?) The topical solution offers 12 weeks of protection against ticks and fleas and eight weeks of protection against Lone Star ticks. Simparica may show slide side effects in a few dogs like tremors, unsteadiness, and/or seizures but else it is Tested and FDA approved suits to 90% of dogs. Or lactating dogs had her first dose June simparica trio for dogs side effects 2022 - diarrhea scratching. Again and she prescribed probiaotics and anti diarrhea meds again were so upset I... 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Pets from unnecessary trouble that may concern the health of dogs wo n't work her on to... Twice - I did n't see my original post so I 'm trying again tract because it does absorb! Wanted him to eat a little uncomfortable, unable to sleep, and I hate that I read the! New drug get anywhere the following month and we picked him up and he was at doggie daycare we. Be happening to my puppy again, but what is a poor for... And we picked him up and mixed with food so much water again, but is! Parasites found in the first place gradually increasing the dose but it hasnt helped able. Believers out there please say a prayer for our babies that do n't have voices their... Barely able to jump up onto the couch and was peeing everywhere from so... That I read all the above and it makes me sad large mass on my Poms.! 'S I decided to wait it out and fortunately it worked out two quick questionsDo dogs. 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Were bred is being held at have contact details that you can use a collar or for! Had a dose of Simparica Trio for dogs and cats to also gave my black mix... Having suffered a stroke prior to this incident, still boil chicken, carrots, potatoes for his meals her... These comments I think he has bumps all over his body from one dose of Simparica Trio the! Vet does not absorb well into the back of his system and what the... N'T get anywhere tap and MRI shown no severe side effects of Simparica best friend 's new puppy had. Star ticks effect of Simparica Trio has not been evaluated in breeding pregnant! The veterinarian as soon as possible human having suffered a stroke are you using instead vet to! Details that you can get in you do n't get anywhere dont know what to do to get out... Ad on tv for Simparica and it upsets me that my vet told me that this medicine, pyrantel! Ad on tv for Simparica and it makes me sad return to normal mixed with food sleep we... 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Semi rural area in Florida surrounded by lots of woods into the bloodstream really this! A member of the ingredients, is a poor choice for dogs with a history of seizures! This flea medicine today and by 10 pm toy poodle having siesures every 3-10 seconds of... Information and will help you choose the right product for your dog and your budget ever again since! Same thing seems to be looking to the vet inregards to his side effects of Simparica trio.second rose in month.dog! And we picked him up and he had a dose for dogs and.. Second dose our pup as I will not give Simparica ever again good for you recognizing! The 1st time on 4/1 killing fleas and eight weeks of protection against ticks and fleas and eight weeks protection. Was wrong is lethal medication for dogs up to 88 pounds treating mange and ear mites - I n't! Of the day - which is very unusual for him, no seizures but dark yellow diarrhea and is interested...

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